Head to Head Contrast: Twist Bioscience (NASDAQ:TWST) vs. Regenxbio (NASDAQ:RGNX)

Twist Bioscience (NASDAQ:TWST) and Regenxbio (NASDAQ:RGNX) are both small-cap medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their analyst recommendations, dividends, profitability, earnings, institutional ownership, valuation and risk.


This table compares Twist Bioscience and Regenxbio’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Twist Bioscience N/A N/A N/A
Regenxbio -41.99% -9.90% -9.35%

Institutional and Insider Ownership

21.4% of Twist Bioscience shares are owned by institutional investors. Comparatively, 81.7% of Regenxbio shares are owned by institutional investors. 13.8% of Regenxbio shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Earnings & Valuation

This table compares Twist Bioscience and Regenxbio’s top-line revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Twist Bioscience $25.43 million 27.29 -$71.23 million ($25.51) -0.97
Regenxbio $218.51 million 8.09 $99.94 million $2.38 20.28

Regenxbio has higher revenue and earnings than Twist Bioscience. Twist Bioscience is trading at a lower price-to-earnings ratio than Regenxbio, indicating that it is currently the more affordable of the two stocks.

Analyst Ratings

This is a summary of recent ratings and price targets for Twist Bioscience and Regenxbio, as provided by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Twist Bioscience 0 1 3 0 2.75
Regenxbio 1 1 5 0 2.57

Twist Bioscience currently has a consensus target price of $26.33, suggesting a potential upside of 6.36%. Regenxbio has a consensus target price of $84.18, suggesting a potential upside of 74.39%. Given Regenxbio’s higher possible upside, analysts plainly believe Regenxbio is more favorable than Twist Bioscience.


Regenxbio beats Twist Bioscience on 8 of the 13 factors compared between the two stocks.

About Twist Bioscience

Twist Bioscience Corporation, a synthetic biology company, manufactures and sells synthetic DNA-based products. The company's DNA synthesis platform enables the manufacturing of synthetic DNA by writing DNA on a silicon chip. It offers synthetic DNA-based products, including synthetic genes, tools for sample preparation, antibody libraries for drug discovery and development, and DNA as a digital data storage medium. Twist Bioscience Corporation has a collaboration agreement with Pandion Therapeutics, Inc. to apply its antibody optimization platform for a targeting arm of a bispecific antibody. The company was founded in 2013 and is headquartered in San Francisco, California.

About Regenxbio

REGENXBIO Inc., a clinical-stage biotechnology company, provides gene therapy product candidates to deliver genes to cells to address genetic defects or to enable cells in the body to produce therapeutic proteins or antibodies that are intended to impact disease. Its gene therapy product candidates are based on NAV Technology Platform, a proprietary adeno-associated virus (AAV) gene delivery platform. The company's lead product candidate is RGX-314, which is in Phase I/IIa clinical trials for the treatment of wet age-related macular degeneration. It is also developing RGX-121 that is in Phase I/II clinical trials to treat mucopolysaccharidosis type II; RGX-111 for treating mucopolysaccharidosis type I; RGX-181 for the treatment of late infantile neuronal ceroid lipofuscinosis type II disease; and RGX-501, which is in Phase I/II clinical trials to treat homozygous familial hypercholesterolemia. REGENXBIO Inc. also licenses its NAV Technology Platform to other biotechnology and pharmaceutical companies. The company was formerly known as REGENX Biosciences, LLC and changed its name to REGENXBIO Inc. in September 2014. REGENXBIO Inc. was founded in 2008 and is headquartered in Rockville, Maryland.

Receive News & Ratings for Twist Bioscience Daily - Enter your email address below to receive a concise daily summary of the latest news and analysts' ratings for Twist Bioscience and related companies with MarketBeat.com's FREE daily email newsletter.