KPTI has been the topic of several other research reports. Zacks Investment Research downgraded Karyopharm Therapeutics from a hold rating to a sell rating in a report on Saturday, March 2nd. BidaskClub raised Karyopharm Therapeutics from a strong sell rating to a sell rating in a report on Wednesday, March 20th. HC Wainwright reissued a buy rating on shares of Karyopharm Therapeutics in a report on Wednesday, February 27th. JPMorgan Chase & Co. downgraded Karyopharm Therapeutics from an overweight rating to a neutral rating and cut their price objective for the company from $21.00 to $7.00 in a report on Friday, March 1st. Finally, Wedbush cut their price objective on Karyopharm Therapeutics from $19.00 to $14.00 and set an outperform rating on the stock in a report on Monday, February 25th. Three investment analysts have rated the stock with a sell rating, two have issued a hold rating and five have assigned a buy rating to the stock. Karyopharm Therapeutics currently has an average rating of Hold and a consensus target price of $17.75.
Shares of KPTI opened at $5.79 on Monday. Karyopharm Therapeutics has a 52-week low of $3.92 and a 52-week high of $21.71. The company has a current ratio of 6.19, a quick ratio of 6.19 and a debt-to-equity ratio of 0.98.
In related news, major shareholder Ltd Chione sold 1,481,643 shares of the firm’s stock in a transaction on Wednesday, February 27th. The stock was sold at an average price of $4.81, for a total transaction of $7,126,702.83. The transaction was disclosed in a filing with the SEC, which is accessible through the SEC website. Company insiders own 13.26% of the company’s stock.
A number of institutional investors and hedge funds have recently made changes to their positions in KPTI. Bank of New York Mellon Corp lifted its holdings in Karyopharm Therapeutics by 2.1% during the 3rd quarter. Bank of New York Mellon Corp now owns 218,594 shares of the company’s stock worth $3,723,000 after buying an additional 4,576 shares during the period. AQR Capital Management LLC lifted its holdings in Karyopharm Therapeutics by 60.6% during the 3rd quarter. AQR Capital Management LLC now owns 30,767 shares of the company’s stock worth $524,000 after buying an additional 11,614 shares during the period. Federated Investors Inc. PA lifted its holdings in Karyopharm Therapeutics by 11,995.4% during the 3rd quarter. Federated Investors Inc. PA now owns 295,854 shares of the company’s stock worth $5,038,000 after buying an additional 293,408 shares during the period. IFP Advisors Inc lifted its holdings in Karyopharm Therapeutics by 197.4% during the 4th quarter. IFP Advisors Inc now owns 5,650 shares of the company’s stock worth $52,000 after buying an additional 3,750 shares during the period. Finally, Emerald Advisers LLC lifted its holdings in Karyopharm Therapeutics by 109.8% during the 4th quarter. Emerald Advisers LLC now owns 1,456,473 shares of the company’s stock worth $13,647,000 after buying an additional 762,405 shares during the period. 87.72% of the stock is currently owned by hedge funds and other institutional investors.
About Karyopharm Therapeutics
Karyopharm Therapeutics Inc, a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of drugs directed against nuclear transport and related targets for the treatment of cancer and other diseases. Its lead drug candidate is Selinexor(KPT-330), which is in Phase IIb clinical study in treatments of refractory multiple myeloma; Phase Ib/II clinical study in combination with backbone treatments for multiple myeloma patients; Phase III clinical trial in combination with Velcade (bortezomib) and dexamethasone for multiple myeloma patients; Phase IIb clinical study in diffuse large B-cell lymphoma; Phase II/III clinical study in liposarcoma; Phase III clinical trial in endometrial cancer; and Phase II clinical trial in glioblastoma multiforme.
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